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Physical Limits on Cooperative Protein-DNA Binding and the Kinetics of Combinatorial Transcription Regulation
Much of the complexity observed in gene regulation originates from cooperative protein-DNA binding. Although studies of the target search of proteins for their specific binding sites on the DNA have revealed design principles for the quantitative characteristics of protein-DNA interactions, no such...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183818/ https://ncbi.nlm.nih.gov/pubmed/21961582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.041 |
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