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Accurate Prediction of Gene Expression by Integration of DNA Sequence Statistics with Detailed Modeling of Transcription Regulation

Gene regulation involves a hierarchy of events that extend from specific protein-DNA interactions to the combinatorial assembly of nucleoprotein complexes. The effects of DNA sequence on these processes have typically been studied based either on its quantitative connection with single-domain bindin...

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Detalhes bibliográficos
Autor principal: Vilar, Jose M.G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955415/
https://ncbi.nlm.nih.gov/pubmed/20959080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.006
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