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Mathematical Model of the Drosophila Circadian Clock: Loop Regulation and Transcriptional Integration

Eukaryotic circadian clocks include interconnected positive and negative feedback loops. The clock-cycle dimer (CLK-CYC) and its homolog, CLK-BMAL1, are key transcriptional activators of central components of the Drosophila and mammalian circadian networks, respectively. In Drosophila, negative loop...

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Sonraí Bibleagrafaíochta
Main Authors: Fathallah-Shaykh, Hassan M., Bona, Jerry L., Kadener, Sebastian
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770617/
https://ncbi.nlm.nih.gov/pubmed/19883582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.018
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