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Mathematical Model of the Drosophila Circadian Clock: Loop Regulation and Transcriptional Integration
Eukaryotic circadian clocks include interconnected positive and negative feedback loops. The clock-cycle dimer (CLK-CYC) and its homolog, CLK-BMAL1, are key transcriptional activators of central components of the Drosophila and mammalian circadian networks, respectively. In Drosophila, negative loop...
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Main Authors: | , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
The Biophysical Society
2009
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770617/ https://ncbi.nlm.nih.gov/pubmed/19883582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.018 |
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