Identification of macrophage liver X receptors as inhibitors of atherosclerosis

Recent studies have identified the liver X receptors (LXRα and LXRβ) as important regulators of cholesterol metabolism and transport. LXRs control transcription of genes critical to a range of biological functions including regulation of high density lipoprotein cholesterol metabolism, hepatic chole...

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Autors principals: Tangirala, Rajendra K., Bischoff, Eric D., Joseph, Sean B., Wagner, Brandee L., Walczak, Robert, Laffitte, Bryan A., Daige, Chris L., Thomas, Diane, Heyman, Richard A., Mangelsdorf, David J., Wang, Xuping, Lusis, Aldons J., Tontonoz, Peter, Schulman, Ira G.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC129365/
https://ncbi.nlm.nih.gov/pubmed/12193651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182199799
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