Transactivation by Retinoid X Receptor–Peroxisome Proliferator-Activated Receptor γ (PPARγ) Heterodimers: Intermolecular Synergy Requires Only the PPARγ Hormone-Dependent Activati...

Por Schulman, Ira G., Shao, Gang, Heyman, Richard A.
Publicado em 1998

Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols

Por Lala, Deepak S., Syka, Peter M., Lazarchik, Steven B., Mangelsdorf, David J., Parker, Keith L., Heyman, Richard A.
Publicado em 1997

Retinoid X Receptor (RXR) Agonist-Induced Activation of Dominant-Negative RXR-Retinoic Acid Receptor α403 Heterodimers Is Developmentally Regulated during Myeloid Differentiation

Por Johnson, Barton S., Chandraratna, Roshantha A. S., Heyman, Richard A., Allegretto, Elizabeth A., Mueller, LeMoyne, Collins, Steven J.
Publicado em 1999

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

Por Watanabe, Mitsuhiro, Houten, Sander M., Wang, Li, Moschetta, Antonio, Mangelsdorf, David J., Heyman, Richard A., Moore, David D., Auwerx, Johan
Publicado em 2004

Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells

Por Wallén-Mackenzie, Åsa, Mata de Urquiza, Alexander, Petersson, Susanna, Rodriguez, Francisco J., Friling, Stina, Wagner, Joseph, Ordentlich, Peter, Lengqvist, Johan, Heyman, Richard A., Arenas, Ernest, Perlmann, Thomas
Publicado em 2003

Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor

Por Claudel, Thierry, Leibowitz, Mark D., Fiévet, Catherine, Tailleux, Anne, Wagner, Brandee, Repa, Joyce J., Torpier, Gérard, Lobaccaro, Jean-Marc, Paterniti, James R., Mangelsdorf, David J., Heyman, Richard A., Auwerx, Johan
Publicado em 2001

Promoter-Specific Roles for Liver X Receptor/Corepressor Complexes in the Regulation of ABCA1 and SREBP1 Gene Expression

Por Wagner, Brandee L., Valledor, Annabel F., Shao, Gang, Daige, Chris L., Bischoff, Eric D., Petrowski, Mary, Jepsen, Kristen, Baek, Sung Hee, Heyman, Richard A., Rosenfeld, Michael G., Schulman, Ira G., Glass, Christopher K.
Publicado em 2003

Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

Por Mootha, Vamsi K., Handschin, Christoph, Arlow, Dan, Xie, Xiaohui, St. Pierre, Julie, Sihag, Smita, Yang, Wenli, Altshuler, David, Puigserver, Pere, Patterson, Nick, Willy, Patricia J., Schulman, Ira G., Heyman, Richard A., Lander, Eric S., Spiegelman, Bruce M.
Publicado em 2004

Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand

Por Willy, Patricia J., Murray, Ian R., Qian, Jing, Busch, Brett B., Stevens, William C., Martin, Richard, Mohan, Raju, Zhou, Sihong, Ordentlich, Peter, Wei, Ping, Sapp, Douglas W., Horlick, Robert A., Heyman, Richard A., Schulman, Ira G.
Publicado em 2004

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

Por Tangirala, Rajendra K., Bischoff, Eric D., Joseph, Sean B., Wagner, Brandee L., Walczak, Robert, Laffitte, Bryan A., Daige, Chris L., Thomas, Diane, Heyman, Richard A., Mangelsdorf, David J., Wang, Xuping, Lusis, Aldons J., Tontonoz, Peter, Schulman, Ira G.
Publicado em 2002

ARN-509: a novel anti-androgen for prostate cancer treatment

Por Clegg, Nicola J., Wongvipat, John, Joseph, Jim, Tran, Chris, Ouk, Samedy, Dilhas, Anna, Chen, Yu, Grillot, Kate, Bischoff, Eric D., Cai, Ling, Aparicio, Anna, Dorow, Steven, Arora, Vivek, Shao, Gang, Qian, Jing, Zhao, Hong, Yang, Guangbin, Cao, Chunyan, Sensintaffar, John, Wasielewska, Teresa, Herbert, Mark R., Bonnefous, Celine, Darimont, Beatrice, Scher, Howard I., Smith-Jones, Peter, Klang, Mark, Smith, Nicholas D., De Stanchina, Elisa, Wu, Nian, Ouerfelli, Ouathek, Rix, Peter J., Heyman, Richard A., Jung, Michael E., Sawyers, Charles L., Hager, Jeffrey H.
Publicado em 2012

The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

Por Joseph, James D, Darimont, Beatrice, Zhou, Wei, Arrazate, Alfonso, Young, Amy, Ingalla, Ellen, Walter, Kimberly, Blake, Robert A, Nonomiya, Jim, Guan, Zhengyu, Kategaya, Lorna, Govek, Steven P, Lai, Andiliy G, Kahraman, Mehmet, Brigham, Dan, Sensintaffar, John, Lu, Nhin, Shao, Gang, Qian, Jing, Grillot, Kate, Moon, Michael, Prudente, Rene, Bischoff, Eric, Lee, Kyoung-Jin, Bonnefous, Celine, Douglas, Karensa L, Julien, Jackaline D, Nagasawa, Johnny Y, Aparicio, Anna, Kaufman, Josh, Haley, Benjamin, Giltnane, Jennifer M, Wertz, Ingrid E, Lackner, Mark R, Nannini, Michelle A, Sampath, Deepak, Schwarz, Luis, Manning, Henry Charles, Tantawy, Mohammed Noor, Arteaga, Carlos L, Heyman, Richard A, Rix, Peter J, Friedman, Lori, Smith, Nicholas D, Metcalfe, Ciara, Hager, Jeffrey H
Publicado no eLife (2016)