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Identification of macrophage liver X receptors as inhibitors of atherosclerosis

Recent studies have identified the liver X receptors (LXRα and LXRβ) as important regulators of cholesterol metabolism and transport. LXRs control transcription of genes critical to a range of biological functions including regulation of high density lipoprotein cholesterol metabolism, hepatic chole...

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Detalhes bibliográficos
Main Authors: Tangirala, Rajendra K., Bischoff, Eric D., Joseph, Sean B., Wagner, Brandee L., Walczak, Robert, Laffitte, Bryan A., Daige, Chris L., Thomas, Diane, Heyman, Richard A., Mangelsdorf, David J., Wang, Xuping, Lusis, Aldons J., Tontonoz, Peter, Schulman, Ira G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129365/
https://ncbi.nlm.nih.gov/pubmed/12193651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182199799
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