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Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates

We have examined the kinetics of processing of the HIV-1 Gag-Pro-Pol precursor in an in vitro assay with mature protease added in trans. The processing sites were cleaved at different rates to produce distinct intermediates. The initial cleavage occurred at the p2/NC site. Intermediate cleavages occ...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Pettit, Steve C, Lindquist, Jeffrey N, Kaplan, Andrew H, Swanstrom, Ronald
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291402/
https://ncbi.nlm.nih.gov/pubmed/16262906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-66
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