New Class of Competitive Inhibitor of Bacterial Histidine Kinases

Bacterial histidine kinases have been proposed as targets for the discovery of new antibiotics, yet few specific inhibitors of bacterial histidine kinases have been reported. We report here a novel thienopyridine (TEP) compound that inhibits bacterial histidine kinases competitively with respect to...

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Hlavní autoři: Gilmour, Raymond, Foster, J. Estelle, Sheng, Qin, McClain, Jonathan R., Riley, Anna, Sun, Pei-Ming, Ng, Wai-Leung, Yan, Dalai, Nicas, Thalia I., Henry, Kenneth, Winkler, Malcolm E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291283/
https://ncbi.nlm.nih.gov/pubmed/16291694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.23.8196-8200.2005
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