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Regulation of the pspA Virulence Factor and Essential pcsB Murein Biosynthetic Genes by the Phosphorylated VicR (YycF) Response Regulator in Streptococcus pneumoniae

The VicRK (YycFG) two-component regulatory system (TCS) is required for virulence of the human respiratory pathogen Streptococcus pneumoniae (pneumococcus). The VicR (YycF) response regulator (RR) is essential through its positive regulation of pcsB, which encodes an extracellular protein that media...

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Библиографические подробности
Главные авторы: Ng, Wai-Leung, Tsui, Ho-Ching Tiffany, Winkler, Malcolm E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1272996/
https://ncbi.nlm.nih.gov/pubmed/16237028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.21.7444-7459.2005
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