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Regulation of the pspA Virulence Factor and Essential pcsB Murein Biosynthetic Genes by the Phosphorylated VicR (YycF) Response Regulator in Streptococcus pneumoniae

The VicRK (YycFG) two-component regulatory system (TCS) is required for virulence of the human respiratory pathogen Streptococcus pneumoniae (pneumococcus). The VicR (YycF) response regulator (RR) is essential through its positive regulation of pcsB, which encodes an extracellular protein that media...

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Bibliografske podrobnosti
Main Authors: Ng, Wai-Leung, Tsui, Ho-Ching Tiffany, Winkler, Malcolm E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1272996/
https://ncbi.nlm.nih.gov/pubmed/16237028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.21.7444-7459.2005
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