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New Class of Competitive Inhibitor of Bacterial Histidine Kinases

Bacterial histidine kinases have been proposed as targets for the discovery of new antibiotics, yet few specific inhibitors of bacterial histidine kinases have been reported. We report here a novel thienopyridine (TEP) compound that inhibits bacterial histidine kinases competitively with respect to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gilmour, Raymond, Foster, J. Estelle, Sheng, Qin, McClain, Jonathan R., Riley, Anna, Sun, Pei-Ming, Ng, Wai-Leung, Yan, Dalai, Nicas, Thalia I., Henry, Kenneth, Winkler, Malcolm E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291283/
https://ncbi.nlm.nih.gov/pubmed/16291694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.23.8196-8200.2005
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