New Class of Competitive Inhibitor of Bacterial Histidine Kinases

Bacterial histidine kinases have been proposed as targets for the discovery of new antibiotics, yet few specific inhibitors of bacterial histidine kinases have been reported. We report here a novel thienopyridine (TEP) compound that inhibits bacterial histidine kinases competitively with respect to...

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Detalhes bibliográficos
Main Authors: Gilmour, Raymond, Foster, J. Estelle, Sheng, Qin, McClain, Jonathan R., Riley, Anna, Sun, Pei-Ming, Ng, Wai-Leung, Yan, Dalai, Nicas, Thalia I., Henry, Kenneth, Winkler, Malcolm E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291283/
https://ncbi.nlm.nih.gov/pubmed/16291694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.23.8196-8200.2005
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