Werner Protein Protects Nonproliferating Cells from Oxidative DNA Damage

Werner syndrome, caused by mutations of the WRN gene, mimics many changes of normal aging. Although roles for WRN protein in DNA replication, recombination, and telomere maintenance have been suggested, the pathology of rapidly dividing cells is not a feature of Werner syndrome. To identify cellular...

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Autors principals: Szekely, Anna M., Bleichert, Franziska, Nümann, Astrid, Van Komen, Stephen, Manasanch, Elisabeth, Ben Nasr, Abdelhakim, Canaan, Allon, Weissman, Sherman M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291253/
https://ncbi.nlm.nih.gov/pubmed/16287861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10492-10506.2005
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