Werner Protein Protects Nonproliferating Cells from Oxidative DNA Damage

Werner syndrome, caused by mutations of the WRN gene, mimics many changes of normal aging. Although roles for WRN protein in DNA replication, recombination, and telomere maintenance have been suggested, the pathology of rapidly dividing cells is not a feature of Werner syndrome. To identify cellular...

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Bibliographische Detailangaben
Hauptverfasser: Szekely, Anna M., Bleichert, Franziska, Nümann, Astrid, Van Komen, Stephen, Manasanch, Elisabeth, Ben Nasr, Abdelhakim, Canaan, Allon, Weissman, Sherman M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291253/
https://ncbi.nlm.nih.gov/pubmed/16287861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10492-10506.2005
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