Werner Protein Protects Nonproliferating Cells from Oxidative DNA Damage

Werner syndrome, caused by mutations of the WRN gene, mimics many changes of normal aging. Although roles for WRN protein in DNA replication, recombination, and telomere maintenance have been suggested, the pathology of rapidly dividing cells is not a feature of Werner syndrome. To identify cellular...

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Autores principales: Szekely, Anna M., Bleichert, Franziska, Nümann, Astrid, Van Komen, Stephen, Manasanch, Elisabeth, Ben Nasr, Abdelhakim, Canaan, Allon, Weissman, Sherman M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291253/
https://ncbi.nlm.nih.gov/pubmed/16287861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10492-10506.2005
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