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Regulation of Caspase 9 through Phosphorylation by Protein Kinase C Zeta in Response to Hyperosmotic Stress

Caspase 9 is a critical component of the mitochondrial or intrinsic apoptotic pathway and is activated by Apaf-1 following release of cytochrome c from mitochondria in response to a variety of stimuli. Caspase 9 cleaves and activates effector caspases, mainly caspase 3, leading to the demise of the...

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Detalhes bibliográficos
Main Authors: Brady, Suzanne C., Allan, Lindsey A., Clarke, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291226/
https://ncbi.nlm.nih.gov/pubmed/16287866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10543-10555.2005
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