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Phosphorylation by protein kinase A disassembles the caspase-9 core
Caspases, the cysteine proteases which facilitate the faithful execution of apoptosis, are tightly regulated by a number of mechanisms including phosphorylation. In response to cAMP, PKA phosphorylates caspase-9 at three sites preventing caspase-9 activation, and suppressing apoptosis progression. P...
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| Udgivet i: | Cell Death Differ |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5988757/ https://ncbi.nlm.nih.gov/pubmed/29352269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0052-9 |
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