A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

Lignende værker

• A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1
  af: Frödin, Morten, et al.
  Udgivet: (2000)
• Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation
  af: Hauge, Camilla, et al.
  Udgivet: (2007)
• The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB
  af: Biondi, Ricardo M., et al.
  Udgivet: (2001)
• Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C–terminal residues of PKA
  af: Biondi, Ricardo M., et al.
  Udgivet: (2000)
• Activation of p90(Rsk1) Is Sufficient for Differentiation of PC12 Cells
  af: Silverman, Eran, et al.
  Udgivet: (2004)