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Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation
The growth factor/insulin-stimulated AGC kinases share an activation mechanism based on three phosphorylation sites. Of these, only the role of the activation loop phosphate in the kinase domain and the hydrophobic motif (HM) phosphate in a C-terminal tail region are well characterized. We investiga...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1864980/ https://ncbi.nlm.nih.gov/pubmed/17446865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601682 |
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