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Activation of p90(Rsk1) Is Sufficient for Differentiation of PC12 Cells

We investigated the role of Rsk proteins in the nerve growth factor (NGF) signaling pathway in PC12 cells. When rat Rsk1 or murine Rsk2 proteins were transiently expressed, NGF treatment (100 ng/ml for 3 days) caused three- and fivefold increases in Rsk1 and Rsk2 activities, respectively. Increased...

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Autors principals: Silverman, Eran, Frödin, Morten, Gammeltoft, Steen, Maller, James L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC533971/
https://ncbi.nlm.nih.gov/pubmed/15572664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10573-10583.2004
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