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Activation of p90(Rsk1) Is Sufficient for Differentiation of PC12 Cells

We investigated the role of Rsk proteins in the nerve growth factor (NGF) signaling pathway in PC12 cells. When rat Rsk1 or murine Rsk2 proteins were transiently expressed, NGF treatment (100 ng/ml for 3 days) caused three- and fivefold increases in Rsk1 and Rsk2 activities, respectively. Increased...

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Detalhes bibliográficos
Main Authors: Silverman, Eran, Frödin, Morten, Gammeltoft, Steen, Maller, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533971/
https://ncbi.nlm.nih.gov/pubmed/15572664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10573-10583.2004
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