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Complex Functions of AP-1 Transcription Factors in Differentiation and Survival of PC12 Cells

c-Jun activation by mitogen-activated protein kinases has been implicated in various cellular signal responses. We investigated how JNK and c-Jun contribute to neuronal differentiation, cell survival, and apoptosis. In differentiated PC12 cells, JNK signaling can induce apoptosis and c-Jun mediates...

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Detalhes bibliográficos
Main Authors: Leppä, Sirpa, Eriksson, Minna, Saffrich, Rainer, Ansorge, Wilhelm, Bohmann, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87096/
https://ncbi.nlm.nih.gov/pubmed/11390664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.13.4369-4378.2001
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