Interaction of Avilamycin with Ribosomes and Resistance Caused by Mutations in 23S rRNA

The antibiotic growth promoter avilamycin inhibits protein synthesis by binding to bacterial ribosomes. Here the binding site is further characterized on Escherichia coli ribosomes. The drug interacts with domain V of 23S rRNA, giving a chemical footprint at nucleotides A2482 and A2534. Selection of...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Kofoed, Christine B., Vester, Birte
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Mechanisms of Action: Physiological Effects
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384333/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3339-3342.2002
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