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M-CSF mediates TNF-induced inflammatory osteolysis
TNF-α is the dominant cytokine in inflammatory osteolysis. Using mice whose BM stromal cells and osteoclast precursors are chimeric for the presence of TNF receptors, we found that both cell types mediated the cytokine’s osteoclastogenic properties. The greater contribution was made, however, by str...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283943/ https://ncbi.nlm.nih.gov/pubmed/16294221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26132 |
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