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Age-related changes of nuclear architecture in Caenorhabditis elegans

Mutations in lamins cause premature aging syndromes in humans, including the Hutchinson–Gilford Progeria Syndrome (HGPS) and Atypical Werner Syndrome. It has been shown that HGPS cells in culture undergo age-dependent progressive changes in nuclear architecture. However, it is unknown whether simila...

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Détails bibliographiques
Auteurs principaux: Haithcock, Erin, Dayani, Yaron, Neufeld, Ester, Zahand, Adam J., Feinstein, Naomi, Mattout, Anna, Gruenbaum, Yosef, Liu, Jun
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283819/
https://ncbi.nlm.nih.gov/pubmed/16269543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506955102
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