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Age-related changes of nuclear architecture in Caenorhabditis elegans

Mutations in lamins cause premature aging syndromes in humans, including the Hutchinson–Gilford Progeria Syndrome (HGPS) and Atypical Werner Syndrome. It has been shown that HGPS cells in culture undergo age-dependent progressive changes in nuclear architecture. However, it is unknown whether simila...

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Detalhes bibliográficos
Main Authors: Haithcock, Erin, Dayani, Yaron, Neufeld, Ester, Zahand, Adam J., Feinstein, Naomi, Mattout, Anna, Gruenbaum, Yosef, Liu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283819/
https://ncbi.nlm.nih.gov/pubmed/16269543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506955102
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