Ce-emerin and LEM-2: essential roles in Caenorhabditis elegans development, muscle function, and mitosis

Emerin and LEM2 are ubiquitous inner nuclear membrane proteins conserved from humans to Caenorhabditis elegans. Loss of human emerin causes Emery-Dreifuss muscular dystrophy (EDMD). To test the roles of emerin and LEM2 in somatic cells, we used null alleles of both genes to generate C. elegans anima...

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Huvudupphovsmän: Barkan, Rachel, Zahand, Adam J., Sharabi, Kfir, Lamm, Ayelet T., Feinstein, Naomi, Haithcock, Erin, Wilson, Katherine L., Liu, Jun, Gruenbaum, Yosef
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279384/
https://ncbi.nlm.nih.gov/pubmed/22171324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-06-0505
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