Matefin/SUN-1 is a nuclear envelope receptor for CED-4 during Caenorhabditis elegans apoptosis

In Caenorhabditis elegans, the antiapoptotic protein CED-9 is localized at the mitochondria, where it binds the proapoptotic protein CED-4. Induction of apoptosis begins when the proapoptotic protein EGL-1 is expressed and binds CED-9. The binding of EGL-1 to CED-9 releases CED-4 from CED-9 and caus...

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Bibliographic Details
Main Authors: Tzur, Yonatan B., Margalit, Ayelet, Melamed-Book, Naomi, Gruenbaum, Yosef
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569175/
https://ncbi.nlm.nih.gov/pubmed/16938876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604224103
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