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Detection of functional single-nucleotide polymorphisms that affect apoptosis

Human EBV-transformed B lymphocyte cell lines (LCLs) were used to measure the apoptotic response of individuals to γ radiation. The responses form a normal distribution around a median of 35.5% apoptosis with a range of 12-58%. This heterogeneous response has a genetic basis. LCLs from Caucasian don...

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Main Authors: Harris, Sandra L., Gil, German, Robins, Harlan, Hu, Wenwei, Hirshfield, Kim, Bond, Elisabeth, Bond, Gareth, Levine, Arnold J.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283473/
https://ncbi.nlm.nih.gov/pubmed/16260726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508390102
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