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Low-frequency normal mode in DNA HhaI methyltransferase and motions of residues involved in the base flipping

The results of normal-mode analyses are in accord with the proposal that a low-frequency motion of the HhaI methyltransferase enzyme is responsible for base flipping in bound DNA. The vectors of the low-frequency normal mode of residues Ser-85 and Ile-86 point directly to the phosphate and ribose mo...

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Библиографические подробности
Главные авторы: Luo, Jia, Bruice, Thomas C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283451/
https://ncbi.nlm.nih.gov/pubmed/16236720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507913102
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