Interleukin-4 Receptor α Chain and STAT6 Signaling Inhibit Gamma Interferon but Not Th2 Cytokine Expression within Schistosome Granulomas

Compared to wild-type (WT) mice, schistosome granulomas in Stat6 knockout (KO) mice lacked eosinophils and had Th1 features. Interleukin-4 (IL-4) acts through Stat6 in assisting Th2 cell development. The importance of Stat6 for Th2-cell development within schistosome granulomas had not been explored...

Descripció completa

Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Metwali, Ahmed, Blum, Arthur, Elliott, David E., Weinstock, Joel V.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Fungal and Parasitic Infections
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12228294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.10.5651-5658.2002
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!