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Impaired DNA Replication within Progenitor Cell Pools Promotes Leukemogenesis

Impaired cell cycle progression can be paradoxically associated with increased rates of malignancies. Using retroviral transduction of bone marrow progenitors followed by transplantation into mice, we demonstrate that inhibition of hematopoietic progenitor cell proliferation impairs competition, pro...

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Bibliografiska uppgifter
Huvudupphovsmän: Bilousova, Ganna, Marusyk, Andriy, Porter, Christopher C, Cardiff, Robert D, DeGregori, James
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283331/
https://ncbi.nlm.nih.gov/pubmed/16277552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030401
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