Epitope Mapping of the Immunodominant Antigen TB10.4 and the Two Homologous Proteins TB10.3 and TB12.9, Which Constitute a Subfamily of the esat-6 Gene Family

The human T-cell recognition of the low-molecular-mass culture filtrate antigen TB10.4 was evaluated in detail. The molecule was strongly recognized by T cells isolated from tuberculosis (TB) patients and from BCG-vaccinated donors. The epitopes on TB10.4 were mapped with overlapping peptides and fo...

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Autori principali: Skjøt, Rikke Louise Vinther, Brock, Inger, Arend, Sandra M., Munk, Martin E., Theisen, Michael, Ottenhoff, Tom H. M., Andersen, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Bacterial Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128304/
https://ncbi.nlm.nih.gov/pubmed/12228269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.10.5446-5453.2002
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