Analysis of Serum Cross-Reactivity and Cross-Protection Elicited by Immunization with DNA Vaccines against Streptococcus pneumoniae Expressing PspA Fragments from Different Clades

Streptococcus pneumoniae is a major cause of disease, especially in developing countries, and cost-effective alternatives to the currently licensed vaccines are needed. We constructed DNA vaccines based on pneumococcal surface protein A (PspA), an antigen shown to induce protection against pneumococ...

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Main Authors: Miyaji, Eliane N., Ferreira, Daniela M., Lopes, Alexandre P. Y., Brandileone, M. Cristina C., Dias, Waldely O., Leite, Luciana C. C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC128265/
https://ncbi.nlm.nih.gov/pubmed/12183557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5086-5090.2002
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