Immunization of Mice with Single PspA Fragments Induces Antibodies Capable of Mediating Complement Deposition on Different Pneumococcal Strains and Cross-Protection

PspA is an important candidate for a vaccine with serotype-independent immunity against pneumococcal infections. Based on sequence relatedness, PspA has been classified into three families comprising six clades. We have previously addressed the cross-reactivity of antibodies against PspA fragments c...

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Detalhes bibliográficos
Main Authors: Moreno, Adriana T., Oliveira, Maria Leonor S., Ferreira, Daniela M., Ho, Paulo L., Darrieux, Michelle, Leite, Luciana C. C., Ferreira, Jorge M. C., Pimenta, Fabiana C., Andrade, Ana Lúcia S. S., Miyaji, Eliane N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837969/
https://ncbi.nlm.nih.gov/pubmed/20089795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00430-09
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