Genetic Immunization with the Region Encoding the α-Helical Domain of PspA Elicits Protective Immunity against Streptococcus pneumoniae

Pneumococcal surface protein A (PspA) is a pneumococcal virulence factor capable of eliciting protection against pneumococcal infection in mice. Previous studies have demonstrated that the protection is antibody mediated. Here we examined the ability of pspA to elicit a protective immune response fo...

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Detalhes bibliográficos
Main Authors: Bosarge, Joseph R., Watt, James M., McDaniel, D. Olga, Swiatlo, Edwin, McDaniel, Larry S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98657/
https://ncbi.nlm.nih.gov/pubmed/11500417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5456-5463.2001
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