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Genetic Immunization with the Region Encoding the α-Helical Domain of PspA Elicits Protective Immunity against Streptococcus pneumoniae

Pneumococcal surface protein A (PspA) is a pneumococcal virulence factor capable of eliciting protection against pneumococcal infection in mice. Previous studies have demonstrated that the protection is antibody mediated. Here we examined the ability of pspA to elicit a protective immune response fo...

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Main Authors: Bosarge, Joseph R., Watt, James M., McDaniel, D. Olga, Swiatlo, Edwin, McDaniel, Larry S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC98657/
https://ncbi.nlm.nih.gov/pubmed/11500417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.9.5456-5463.2001
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