Relative Roles of Genetic Background and Variation in PspA in the Ability of Antibodies to PspA To Protect against Capsular Type 3 and 4 Strains of Streptococcus pneumoniae

Pneumococcal surface protein A (PspA) is able to elicit antibodies in mice and humans that can protect mice against fatal infection with Streptococcus pneumoniae. It has been observed that immunization with a single family 1 PspA can protect mice against infections with capsular type 3 or 6B strains...

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Main Authors: Roche, Hazeline, Ren, Bing, McDaniel, Larry S., Håkansson, Anders, Briles, David E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC166025/
https://ncbi.nlm.nih.gov/pubmed/12874329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4498-4505.2003
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