Relative Roles of Genetic Background and Variation in PspA in the Ability of Antibodies to PspA To Protect against Capsular Type 3 and 4 Strains of Streptococcus pneumoniae

Pneumococcal surface protein A (PspA) is able to elicit antibodies in mice and humans that can protect mice against fatal infection with Streptococcus pneumoniae. It has been observed that immunization with a single family 1 PspA can protect mice against infections with capsular type 3 or 6B strains...

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Pubblicato in:	Infect Immun
Autori principali:	Roche, Hazeline, Ren, Bing, McDaniel, Larry S., Håkansson, Anders, Briles, David E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4498-4505.2003
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