Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies

Current pneumococcal vaccines are composed of bacterial polysaccharides as antigens, plain or conjugated to carrier proteins. While efficacious against vaccine serotypes, epidemiologic data show an increasing incidence of infections caused by nonvaccine serotypes of Streptococcus pneumoniae. The use...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: da Silva, Míriam A., Converso, Thiago R., Gonçalves, Viviane M., Leite, Luciana C. C., Tanizaki, Martha M., Barazzone, Giovana C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583475/
https://ncbi.nlm.nih.gov/pubmed/28637805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00118-17
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