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Analysis of Serum Cross-Reactivity and Cross-Protection Elicited by Immunization with DNA Vaccines against Streptococcus pneumoniae Expressing PspA Fragments from Different Clades
Streptococcus pneumoniae is a major cause of disease, especially in developing countries, and cost-effective alternatives to the currently licensed vaccines are needed. We constructed DNA vaccines based on pneumococcal surface protein A (PspA), an antigen shown to induce protection against pneumococ...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
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American Society for Microbiology
2002
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Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC128265/ https://ncbi.nlm.nih.gov/pubmed/12183557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5086-5090.2002 |
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