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Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12
DAP12 is a signaling adaptor containing an immunoreceptor tyrosine-based activation motif (ITAM) that pairs with receptors on myeloid cells and natural killer cells. We examine here the responses of mice lacking DAP12 to stimulation through Toll-like receptors (TLRs). Unexpectedly, DAP12-deficient m...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1282462/ https://ncbi.nlm.nih.gov/pubmed/15895090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1204 |
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