Cruzipain Induces Both Mucosal and Systemic Protection against Trypanosoma cruzi in Mice

Cruzipain, the major cysteinyl proteinase of Trypanosoma cruzi, is expressed by all developmental forms and strains of the parasite and stimulates potent humoral and cellular immune responses during infection in both humans and mice. This information suggested that cruzipain could be used to develop...

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Bibliografiske detaljer
Main Authors: Schnapp, Anita R., Eickhoff, Chris S., Sizemore, Donata, Curtiss III, Roy, Hoft, Daniel F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128245/
https://ncbi.nlm.nih.gov/pubmed/12183554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5065-5074.2002
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