Cruzipain Induces Both Mucosal and Systemic Protection against Trypanosoma cruzi in Mice

Cruzipain, the major cysteinyl proteinase of Trypanosoma cruzi, is expressed by all developmental forms and strains of the parasite and stimulates potent humoral and cellular immune responses during infection in both humans and mice. This information suggested that cruzipain could be used to develop...

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Bibliographic Details
Main Authors: Schnapp, Anita R., Eickhoff, Chris S., Sizemore, Donata, Curtiss III, Roy, Hoft, Daniel F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC128245/
https://ncbi.nlm.nih.gov/pubmed/12183554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5065-5074.2002
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