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Cruzipain Induces Both Mucosal and Systemic Protection against Trypanosoma cruzi in Mice

Cruzipain, the major cysteinyl proteinase of Trypanosoma cruzi, is expressed by all developmental forms and strains of the parasite and stimulates potent humoral and cellular immune responses during infection in both humans and mice. This information suggested that cruzipain could be used to develop...

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Autores principales: Schnapp, Anita R., Eickhoff, Chris S., Sizemore, Donata, Curtiss III, Roy, Hoft, Daniel F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC128245/
https://ncbi.nlm.nih.gov/pubmed/12183554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5065-5074.2002
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