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Murine Coronavirus with an Extended Host Range Uses Heparan Sulfate as an Entry Receptor

Only a relatively few mutations in its spike protein allow the murine coronavirus to switch from a murine-restricted tropism to an extended host range by being passaged in vitro. One such virus that we studied had acquired two putative heparan sulfate-binding sites while preserving another site in t...

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Autori principali: de Haan, Cornelis A. M., Li, Zhen, te Lintelo, Eddie, Bosch, Berend Jan, Haijema, Bert Jan, Rottier, Peter J. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280238/
https://ncbi.nlm.nih.gov/pubmed/16254381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14451-14456.2005
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