ATP1A1-Mediated Src Signaling Inhibits Coronavirus Entry into Host Cells

In addition to transporting ions, the multisubunit Na(+),K(+)-ATPase also functions by relaying cardiotonic steroid (CTS)-binding-induced signals into cells. In this study, we analyzed the role of Na(+),K(+)-ATPase and, in particular, of its ATP1A1 α subunit during coronavirus (CoV) infection. As co...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Burkard, Christine, Verheije, Monique H., Haagmans, Bart L., van Kuppeveld, Frank J., Rottier, Peter J. M., Bosch, Berend-Jan, de Haan, Cornelis A. M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442369/
https://ncbi.nlm.nih.gov/pubmed/25653449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03274-14
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