Identification of Interferon-Stimulated Gene 15 as an Antiviral Molecule during Sindbis Virus Infection In Vivo

The innate immune response, and in particular the alpha/beta interferon (IFN-α/β) system, plays a critical role in the control of viral infections. Interferons α and β exert their antiviral effects through the induction of hundreds of interferon-induced (or -stimulated) genes (ISGs). While several o...

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Autors principals: Lenschow, Deborah J., Giannakopoulos, Nadia V., Gunn, Lacey J., Johnston, Christine, O'Guin, Andy K., Schmidt, Robert E., Levine, Beth, Virgin, Herbert W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280211/
https://ncbi.nlm.nih.gov/pubmed/16254333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13974-13983.2005
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