IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

Type I interferons (IFNs) play an essential role in the host response to viral infection through the induction of numerous IFN-stimulated genes (ISGs), including important antiviral molecules such as PKR, RNase L, Mx, and iNOS. Yet, additional antiviral ISGs likely exist. IFN-stimulated gene 15 (ISG...

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Detalhes bibliográficos
Main Authors: Lenschow, Deborah J., Lai, Caroline, Frias-Staheli, Natalia, Giannakopoulos, Nadia V., Lutz, Andrew, Wolff, Thorsten, Osiak, Anna, Levine, Beth, Schmidt, Robert E., García-Sastre, Adolfo, Leib, David A., Pekosz, Andrew, Knobeloch, Klaus-Peter, Horak, Ivan, Virgin, Herbert Whiting
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783119/
https://ncbi.nlm.nih.gov/pubmed/17227866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607038104
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