Natural Killer Cells Utilize both Perforin and Gamma Interferon To Regulate Murine Cytomegalovirus Infection in the Spleen and Liver

Natural killer (NK) cells are critical for innate regulation of the acute phase of murine cytomegalovirus (MCMV) infection and have been reported to utilize perforin (Pfp)- and gamma interferon (IFN-γ)-dependent effector mechanisms in an organ-specific manner to regulate MCMV infection in the spleen...

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Auteurs principaux: Loh, Joy, Chu, Dortha T., O'Guin, Andrew K., Yokoyama, Wayne M., Virgin, Herbert W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC538682/
https://ncbi.nlm.nih.gov/pubmed/15596864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.661-667.2005
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