Natural Killer Cells Utilize both Perforin and Gamma Interferon To Regulate Murine Cytomegalovirus Infection in the Spleen and Liver

Natural killer (NK) cells are critical for innate regulation of the acute phase of murine cytomegalovirus (MCMV) infection and have been reported to utilize perforin (Pfp)- and gamma interferon (IFN-γ)-dependent effector mechanisms in an organ-specific manner to regulate MCMV infection in the spleen...

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Autors principals: Loh, Joy, Chu, Dortha T., O'Guin, Andrew K., Yokoyama, Wayne M., Virgin, Herbert W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538682/
https://ncbi.nlm.nih.gov/pubmed/15596864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.1.661-667.2005
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