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Modulation of the Immune Response to the Severe Acute Respiratory Syndrome Spike Glycoprotein by Gene-Based and Inactivated Virus Immunization

Although the initial isolates of the severe acute respiratory syndrome (SARS) coronavirus (CoV) are sensitive to neutralization by antibodies through their spike (S) glycoprotein, variants of S have since been identified that are resistant to such inhibition. Optimal vaccine strategies would therefo...

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Autori principali: Kong, Wing-pui, Xu, Ling, Stadler, Konrad, Ulmer, Jeffrey B., Abrignani, Sergio, Rappuoli, Rino, Nabel, Gary J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280202/
https://ncbi.nlm.nih.gov/pubmed/16254327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13915-13923.2005
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