Modulation of the Immune Response to the Severe Acute Respiratory Syndrome Spike Glycoprotein by Gene-Based and Inactivated Virus Immunization

Although the initial isolates of the severe acute respiratory syndrome (SARS) coronavirus (CoV) are sensitive to neutralization by antibodies through their spike (S) glycoprotein, variants of S have since been identified that are resistant to such inhibition. Optimal vaccine strategies would therefo...

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Detalhes bibliográficos
Main Authors: Kong, Wing-pui, Xu, Ling, Stadler, Konrad, Ulmer, Jeffrey B., Abrignani, Sergio, Rappuoli, Rino, Nabel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280202/
https://ncbi.nlm.nih.gov/pubmed/16254327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13915-13923.2005
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