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Modulation of the Immune Response to the Severe Acute Respiratory Syndrome Spike Glycoprotein by Gene-Based and Inactivated Virus Immunization

Although the initial isolates of the severe acute respiratory syndrome (SARS) coronavirus (CoV) are sensitive to neutralization by antibodies through their spike (S) glycoprotein, variants of S have since been identified that are resistant to such inhibition. Optimal vaccine strategies would therefo...

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Библиографические подробности
Главные авторы: Kong, Wing-pui, Xu, Ling, Stadler, Konrad, Ulmer, Jeffrey B., Abrignani, Sergio, Rappuoli, Rino, Nabel, Gary J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280202/
https://ncbi.nlm.nih.gov/pubmed/16254327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13915-13923.2005
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