Retroviral Restriction Factor TRIM5α Is a Trimer

The retrovirus restriction factor TRIM5α targets the viral capsid soon after entry. Here we show that the TRIM5α protein oligomerizes into trimers. The TRIM5α coiled-coil and B30.2(SPRY) domains make important contributions to the formation and/or stability of the trimers. A functionally defective T...

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Detalhes bibliográficos
Main Authors: Mische, Claudia C., Javanbakht, Hassan, Song, Byeongwoon, Diaz-Griffero, Felipe, Stremlau, Matthew, Strack, Bettina, Si, Zhihai, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280198/
https://ncbi.nlm.nih.gov/pubmed/16254380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14446-14450.2005
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